Take 2: Prophecy and Monitoring

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Nasopharyngeal carcinoma (NPC), a type of head and neck cancer, can be difficult to diagnose because its symptoms can be similar to that of other illnesses. With the Take 2: Prophecy Test, you can help your patients know if they have an NPC so they have better odds of managing and surviving the disease.

Take2 Test for NPC is the only early cancer screening test for NPC that is validated by a large-scale clinical trial on asymptomatic individuals. It makes use of the latest DNA technologies to detect human and NPC-associated Epstein-Barr Virus (EBV) DNA in the bloodstream. When NPC is present, cancer cells shed viral and human DNA into the blood.

THERE ARE TWO TYPES OF THIS TEST:

  1. Take 2 Prophecy™ Test will determine whether or not the patient has NPC. This test can detect NPC in patients at an earlier stage, when there is a better chance of recovery.
  2. Take 2 Monitoring Test will monitor the number of Epstein-Barr virus (EBV) DNA linked with the condition, after the patient has been diagnosed.

IS YOUR PATIENT SUFFERING FROM:

  • Nosebleed
  • Headache
  • Ringing in the ears
  • Neck swelling
  • One-sided headache
  • Nasal blockage
  • Hearing loss
  • Facial numbness
  • Difficulty swallowing
  • Hoarse voice

These symptoms can be signs of NPC. They resemble many other conditions which is why NPC is tricky to diagnose at the beginning.

Also known as the “Cantonese Cancer,” due to its prevalence in Southern China and Southeast China, NPC can cause 35,000 to 40,000 deaths per year in Asia. Some factors that can make one more prone to NPC include being male, those who are ages 40-74, have a history of NPC, as well as those who have an EBV infection. Lifestyle factors such as smoking, eating more salted fish especially during one’s youth, and occupational exposure to wood dust, formaldehyde, and chemical fumes, can also make one more vulnerable to NPC.

HOW YOU CAN BENEFIT:

  • NPC identification in asymptomatic people has been clinically proven, and it is able to detect early-stage NPC and improve your patient’s survival rate (High detection rate of 97.1%)
  • Can be used to screen those hesitant to undergo nasal endoscopy and biopsy (Patients can go for nasoendoscopy/ MRI for confirmation after a positive test result.)
  • A simple blood extraction is required for sample collection

ADVANTAGES OF THE TEST:

  • Founded by world-class scientists from the Chinese University of Hong Kong
  • Uses licensed nasopharyngeal cancer technologies from a leading cancer detection company in Silicon Valley, USA
  • More accurate blood-based screening test with a Low False Positive Rate (0.7%) and a Positive Predictive Value (PPV):19.5%
  • Screening and monitoring tests are available

THE SCIENCE BEHIND THE TEST

Take2 works by combining quantitative polymerase chain reaction (qPCR) and Next Generation Sequencing (NGS) technologies to analyze circulating DNA in blood plasma. Advanced computer algorithms are used to assess the data. A single blood draw is required for the sample.

What else do you need to know:

  • Sample: Blood
  • Patients don’t need to fast before the test.

HOW TO AVAIL

  1. The physician recommends the test to the patient.
  2. A key account specialist from LifeScience Center will contact the patient to arrange for the sample collection. They will also address any further concerns they may have about the treatment.
  3. A medical technologist from LifeScience Center will collect the patient’s sample at the agreed-upon place.
  4. The sample will then be arranged for transportation to LifeScience Center’s international partner laboratory.
  5. A key account specialist will get in touch with the physician to discuss the results of the patient’s test.

DETECT NPC EARLY IN PATIENTS AND HELP THEM SURVIVE IT

Through Take 2, early-stage NPC can be detected early, increasing patients’ survival rate. The test uses the latest, most innovative technology to get comprehensive and accurate results. All this, through a simple blood extraction.

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